Testosterone Therapy in Men

Written by Dr. Nirvana

November 12, 2010

During the aging process, what happens to the body that is related to hormone decline? These alterations can include decreased capacity for protein synthesis, decreased immune function, loss of muscle strength and function, fatigue, increased body fat, decreased bone density, erectile dysfunction, decreased libido and mood. These changes lead to age-related disability including less strength, endurance, mobility, energy…better put, a decreased quality of life and vitality. These deleterious effects can be delay or improved by hormone restoration to allow for a healthier and functional state. This is an important aspect of preventative medicine.


By middle age virtually all men experience some decline in testosterone, but only a small percentage of aging men have levels far below those considered normal for their age.  Therefore testosterone should be adjusted to an age-normal level. More benefits are realized when testosterone is replace to a level consistent with highest metabolic function.

Adverse Effects Related to Testosterone Therapy

1.Fluid Retention

2. Liver toxicity

3.Decreased Fertility

4.Sleep Apnea

5.Tender or Enlarged Breasts

6.Prostatic Growth

Cardioprotective Effects of Testosterone Therapy

1.Reduction in pro-inflammatory cellular messenger

2.Increase anti-inflammatory immunity

3.Reduction in cell adhesion molecules promoting vessel fluidity

4. Improves vasodilation and vascular reactivity

5.Lowers LDL concentrations

6.Improves insulin sensitivity

7. Reduces visceral fat mass and body mass indices


DHEA or dehydroepiandtrosterone is produced by the adrenal glands (which are responsible for our fight/flight response). DHEA is derived from pregnenolone, which is metabolized from cholesterol. DHEA can be converted into other sex hormones, including testosterone and estrogen. DHEA reported benefits for patients with diabetes, senile dementia, obesity and autoimmune diseases.

While there are a wide array of treatments for treating testosterone deficiency, the above mentioned are a few of the most popular. A carefully designed protocol that addresses the thyroid, blood glucose levels, and prevention of heart disease not only enhances the quality of life for men; but also assists the body in maintaining optimum function.

For more information on beginning hormone therapy, contact Dr. Nirvana at 949-836-6991.

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